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SMILES: COc1ccc(cc1)-c1cc(C(=O)NC2CC2)c(CN)c(C)n1

InChI Key: InChIKey=HAVYLWDMXRGGTG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339123   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50339123
PNG
(3-(aminomethyl)-N-cyclopropyl-6-(4-methoxyphenyl)-...)
Show SMILES COc1ccc(cc1)-c1cc(C(=O)NC2CC2)c(CN)c(C)n1
Show InChI InChI=1S/C18H21N3O2/c1-11-16(10-19)15(18(22)21-13-5-6-13)9-17(20-11)12-3-7-14(23-2)8-4-12/h3-4,7-9,13H,5-6,10,19H2,1-2H3,(H,21,22)
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n/an/a>5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...

ACS Med Chem Lett 1: 530-535 (2010)


Article DOI: 10.1021/ml100200c
BindingDB Entry DOI: 10.7270/Q2513ZGH
More data for this
Ligand-Target Pair