BDBM50339136 3-(10H-phenothiazin-10-yl)propan-1-amine::3-Phenothiazin-10-yl-propylamine::CHEMBL288110::US9504692, 3985

SMILES: NCCCN1c2ccccc2Sc2ccccc12

InChI Key: InChIKey=OJPDZEFBOMRMTK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GST-MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50339136 (3-(10H-phenothiazin-10-yl)propan-1-amine | 3-Pheno...) Show SMILES NCCCN1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C15H16N2S/c16-10-5-11-17-12-6-1-3-8-14(12)18-15-9-4-2-7-13(15)17/h1-4,6-9H,5,10-11,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	30
HELMHOLTZ ZENTRUM MUNCHEN, DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH) US Patent					Assay Description To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...				US Patent US9504692 (2016) BindingDB Entry DOI: 10.7270/Q21C1VSR
					More data for this Ligand-Target Pair
Pleiotropic ABC efflux transporter of multiple drugs (Saccharomyces cerevisiae S288c)	BDBM50339136 (3-(10H-phenothiazin-10-yl)propan-1-amine | 3-Pheno...) Show SMILES NCCCN1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C15H16N2S/c16-10-5-11-17-12-6-1-3-8-14(12)18-15-9-4-2-7-13(15)17/h1-4,6-9H,5,10-11,16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw Medical University Curated by ChEMBL					Assay Description Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assay				Antimicrob Agents Chemother 53: 1516-27 (2009) Article DOI: 10.1128/AAC.00956-08 BindingDB Entry DOI: 10.7270/Q2125TNZ
					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50339136 (3-(10H-phenothiazin-10-yl)propan-1-amine | 3-Pheno...) Show SMILES NCCCN1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C15H16N2S/c16-10-5-11-17-12-6-1-3-8-14(12)18-15-9-4-2-7-13(15)17/h1-4,6-9H,5,10-11,16H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.41E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductase				J Med Chem 41: 148-56 (1998) Article DOI: 10.1021/jm960814j BindingDB Entry DOI: 10.7270/Q2ZP457X
					More data for this Ligand-Target Pair