BDBM50339895 (S)-1-(1-(2-(5-chlorothiophen-2-yl)pyrimidin-4-yl)piperidin-3-yl)-3-ethyl-1H-benzo[d]imidazol-2(3H)-one::CHEMBL1761298

SMILES: CCn1c2ccccc2n([C@H]2CCCN(C2)c2ccnc(n2)-c2ccc(Cl)s2)c1=O

InChI Key: InChIKey=NGYLGKJFTFTOSD-HNNXBMFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50339895 ((S)-1-(1-(2-(5-chlorothiophen-2-yl)pyrimidin-4-yl)...) Show SMILES CCn1c2ccccc2n([C@H]2CCCN(C2)c2ccnc(n2)-c2ccc(Cl)s2)c1=O |r| Show InChI InChI=1S/C22H22ClN5OS/c1-2-27-16-7-3-4-8-17(16)28(22(27)29)15-6-5-13-26(14-15)20-11-12-24-21(25-20)18-9-10-19(23)30-18/h3-4,7-12,15H,2,5-6,13-14H2,1H3/t15-/m0/s1	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339895 ((S)-1-(1-(2-(5-chlorothiophen-2-yl)pyrimidin-4-yl)...) Show SMILES CCn1c2ccccc2n([C@H]2CCCN(C2)c2ccnc(n2)-c2ccc(Cl)s2)c1=O |r| Show InChI InChI=1S/C22H22ClN5OS/c1-2-27-16-7-3-4-8-17(16)28(22(27)29)15-6-5-13-26(14-15)20-11-12-24-21(25-20)18-9-10-19(23)30-18/h3-4,7-12,15H,2,5-6,13-14H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair