BDBM50340021 6-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1762490

SMILES: CCn1c(CN2C(=O)COc3ccc(Br)cc23)nnc1SCc1ccc(Cl)cc1

InChI Key: InChIKey=AVJUEPCJRQAQLY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50340021 (6-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,...) Show SMILES CCn1c(CN2C(=O)COc3ccc(Br)cc23)nnc1SCc1ccc(Cl)cc1 Show InChI InChI=1S/C20H18BrClN4O2S/c1-2-25-18(23-24-20(25)29-12-13-3-6-15(22)7-4-13)10-26-16-9-14(21)5-8-17(16)28-11-19(26)27/h3-9H,2,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...				Bioorg Med Chem Lett 21: 2472-5 (2011) Article DOI: 10.1016/j.bmcl.2011.02.056 BindingDB Entry DOI: 10.7270/Q25Q4WD2
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50340021 (6-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,...) Show SMILES CCn1c(CN2C(=O)COc3ccc(Br)cc23)nnc1SCc1ccc(Cl)cc1 Show InChI InChI=1S/C20H18BrClN4O2S/c1-2-25-18(23-24-20(25)29-12-13-3-6-15(22)7-4-13)10-26-16-9-14(21)5-8-17(16)28-11-19(26)27/h3-9H,2,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...				Bioorg Med Chem Lett 21: 2472-5 (2011) Article DOI: 10.1016/j.bmcl.2011.02.056 BindingDB Entry DOI: 10.7270/Q25Q4WD2
					More data for this Ligand-Target Pair