BDBM50340275 CHEMBL1760635::N-(6-(2-(3-(3,4-dichlorophenyl)ureido)ethyl)-1H-benzo[d]imidazol-2-yl)acetamide

SMILES: CC(=O)Nc1nc2ccc(CCNC(=O)Nc3ccc(Cl)c(Cl)c3)cc2[nH]1

InChI Key: InChIKey=TVPKYNGLBFIPEN-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340275 (CHEMBL1760635 | N-(6-(2-(3-(3,4-dichlorophenyl)ure...) Show SMILES CC(=O)Nc1nc2ccc(CCNC(=O)Nc3ccc(Cl)c(Cl)c3)cc2[nH]1 Show InChI InChI=1S/C18H17Cl2N5O2/c1-10(26)22-17-24-15-5-2-11(8-16(15)25-17)6-7-21-18(27)23-12-3-4-13(19)14(20)9-12/h2-5,8-9H,6-7H2,1H3,(H2,21,23,27)(H2,22,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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