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SMILES: Cc1ncn(n1)-c1ccc(Nc2ncc3cccc(-c4ccc(C)nc4)c3n2)cc1

InChI Key: InChIKey=GUEKGHGNEKDOMS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340616   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (Human))		BDBM50340616
PNG
(CHEMBL1761571 | N-(4-(3-methyl-1H-1,2,4-triazol-1-...)
Show SMILES Cc1ncn(n1)-c1ccc(Nc2ncc3cccc(-c4ccc(C)nc4)c3n2)cc1
Show InChI InChI=1S/C23H19N7/c1-15-6-7-17(12-24-15)21-5-3-4-18-13-25-23(28-22(18)21)27-19-8-10-20(11-9-19)30-14-26-16(2)29-30/h3-14H,1-2H3,(H,25,27,28)
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n/an/a 30n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK3 by HRTF

Bioorg Med Chem Lett 21: 1719-23 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.079
BindingDB Entry DOI: 10.7270/Q2F1901V
More data for this
Ligand-Target Pair