BDBM50340618 CHEMBL1761573::N-(4-fluorophenyl)-8-(6-methylpyridin-3-yl)quinazolin-2-amine

SMILES: Cc1ccc(cn1)-c1cccc2cnc(Nc3ccc(F)cc3)nc12

InChI Key: InChIKey=CVTJYTULQRZSLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50340618 (CHEMBL1761573 | N-(4-fluorophenyl)-8-(6-methylpyri...) Show SMILES Cc1ccc(cn1)-c1cccc2cnc(Nc3ccc(F)cc3)nc12 Show InChI InChI=1S/C20H15FN4/c1-13-5-6-14(11-22-13)18-4-2-3-15-12-23-20(25-19(15)18)24-17-9-7-16(21)8-10-17/h2-12H,1H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 by HRTF				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair