BDBM50340623 8-chloro-7-(1-isopropyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)quinazolin-2-amine::CHEMBL1761578

SMILES: CC(C)n1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc2c1Cl

InChI Key: InChIKey=PYFMPAWBPVAOQN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor Jun (Homo sapiens (Human))	BDBM50340623 (8-chloro-7-(1-isopropyl-1H-pyrazol-4-yl)-N-(4-(3-m...) Show SMILES CC(C)n1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc2c1Cl Show InChI InChI=1S/C26H26ClN9O/c1-17(2)35-15-19(14-30-35)22-8-3-18-13-28-25(32-24(18)23(22)27)31-20-4-6-21(7-5-20)36-16-29-26(33-36)34-9-11-37-12-10-34/h3-8,13-17H,9-12H2,1-2H3,(H,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of c-Jun				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50340623 (8-chloro-7-(1-isopropyl-1H-pyrazol-4-yl)-N-(4-(3-m...) Show SMILES CC(C)n1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc2c1Cl Show InChI InChI=1S/C26H26ClN9O/c1-17(2)35-15-19(14-30-35)22-8-3-18-13-28-25(32-24(18)23(22)27)31-20-4-6-21(7-5-20)36-16-29-26(33-36)34-9-11-37-12-10-34/h3-8,13-17H,9-12H2,1-2H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 by HRTF				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair