null

SMILES: CCOc1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1

InChI Key: InChIKey=FUMGICOYLBIECG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50341464 (8-(5-Ethoxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyr...) Show SMILES CCOc1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1 Show InChI InChI=1S/C18H18N2O2/c1-2-22-16-9-15(10-19-11-16)14-7-12-3-4-17(21)20-6-5-13(8-14)18(12)20/h7-11H,2-6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay				J Med Chem 54: 2307-19 (2011) Article DOI: 10.1021/jm101470k BindingDB Entry DOI: 10.7270/Q2765FM6
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50341464 (8-(5-Ethoxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyr...) Show SMILES CCOc1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1 Show InChI InChI=1S/C18H18N2O2/c1-2-22-16-9-15(10-19-11-16)14-7-12-3-4-17(21)20-6-5-13(8-14)18(12)20/h7-11H,2-6H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay				J Med Chem 54: 2307-19 (2011) Article DOI: 10.1021/jm101470k BindingDB Entry DOI: 10.7270/Q2765FM6
					More data for this Ligand-Target Pair