null

SMILES: O=C1CCc2cc(cc3CCN1c23)-c1cncnc1

InChI Key: InChIKey=MBQCMTFGARGXAF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50341471 (8-Pyrimidin-5-yl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2...) Show SMILES O=C1CCc2cc(cc3CCN1c23)-c1cncnc1 Show InChI InChI=1S/C15H13N3O/c19-14-2-1-10-5-12(13-7-16-9-17-8-13)6-11-3-4-18(14)15(10)11/h5-9H,1-4H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay				J Med Chem 54: 2307-19 (2011) Article DOI: 10.1021/jm101470k BindingDB Entry DOI: 10.7270/Q2765FM6
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50341471 (8-Pyrimidin-5-yl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2...) Show SMILES O=C1CCc2cc(cc3CCN1c23)-c1cncnc1 Show InChI InChI=1S/C15H13N3O/c19-14-2-1-10-5-12(13-7-16-9-17-8-13)6-11-3-4-18(14)15(10)11/h5-9H,1-4H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay				J Med Chem 54: 2307-19 (2011) Article DOI: 10.1021/jm101470k BindingDB Entry DOI: 10.7270/Q2765FM6
					More data for this Ligand-Target Pair