BDBM50341786 (1S,2R,3R)-1-[(R)-4-(4-Chlorophenyl)-3-methylpiperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766908

SMILES: C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(Cl)cc1)C(O)=O

InChI Key: InChIKey=STTHHFYKRNBSEX-AJYGTSELSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-14 (MMP14) (Homo sapiens (Human))	BDBM50341786 ((1S,2R,3R)-1-[(R)-4-(4-Chlorophenyl)-3-methylpiper...) Show SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C22H26ClN3O4S/c1-15-14-25(12-13-26(15)19-10-8-18(23)9-11-19)31(29,30)24-22(21(27)28)16(2)20(22)17-6-4-3-5-7-17/h3-11,15-16,20,24H,12-14H2,1-2H3,(H,27,28)/t15-,16-,20-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate reader				J Med Chem 54: 2839-63 (2011) Article DOI: 10.1021/jm101609j BindingDB Entry DOI: 10.7270/Q2N87B3D
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50341786 ((1S,2R,3R)-1-[(R)-4-(4-Chlorophenyl)-3-methylpiper...) Show SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C22H26ClN3O4S/c1-15-14-25(12-13-26(15)19-10-8-18(23)9-11-19)31(29,30)24-22(21(27)28)16(2)20(22)17-6-4-3-5-7-17/h3-11,15-16,20,24H,12-14H2,1-2H3,(H,27,28)/t15-,16-,20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant TACE after 60 mins by fluorescence plate reader				J Med Chem 54: 2839-63 (2011) Article DOI: 10.1021/jm101609j BindingDB Entry DOI: 10.7270/Q2N87B3D
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50341786 ((1S,2R,3R)-1-[(R)-4-(4-Chlorophenyl)-3-methylpiper...) Show SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C22H26ClN3O4S/c1-15-14-25(12-13-26(15)19-10-8-18(23)9-11-19)31(29,30)24-22(21(27)28)16(2)20(22)17-6-4-3-5-7-17/h3-11,15-16,20,24H,12-14H2,1-2H3,(H,27,28)/t15-,16-,20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate reader				J Med Chem 54: 2839-63 (2011) Article DOI: 10.1021/jm101609j BindingDB Entry DOI: 10.7270/Q2N87B3D
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50341786 ((1S,2R,3R)-1-[(R)-4-(4-Chlorophenyl)-3-methylpiper...) Show SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C22H26ClN3O4S/c1-15-14-25(12-13-26(15)19-10-8-18(23)9-11-19)31(29,30)24-22(21(27)28)16(2)20(22)17-6-4-3-5-7-17/h3-11,15-16,20,24H,12-14H2,1-2H3,(H,27,28)/t15-,16-,20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate reader				J Med Chem 54: 2839-63 (2011) Article DOI: 10.1021/jm101609j BindingDB Entry DOI: 10.7270/Q2N87B3D
					More data for this Ligand-Target Pair