BDBM50341822 (1S,2R,3R)-1-[4-(4-Chlorophenyl)piperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766906

SMILES: C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1)C(O)=O

InChI Key: InChIKey=GCYXMFHUCWJAKI-VMRPVKRXSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-14 (MMP14) (Homo sapiens (Human))	BDBM50341822 ((1S,2R,3R)-1-[4-(4-Chlorophenyl)piperazine-1-sulfo...) Show SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C21H24ClN3O4S/c1-15-19(16-5-3-2-4-6-16)21(15,20(26)27)23-30(28,29)25-13-11-24(12-14-25)18-9-7-17(22)8-10-18/h2-10,15,19,23H,11-14H2,1H3,(H,26,27)/t15-,19-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate reader				J Med Chem 54: 2839-63 (2011) Article DOI: 10.1021/jm101609j BindingDB Entry DOI: 10.7270/Q2N87B3D
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50341822 ((1S,2R,3R)-1-[4-(4-Chlorophenyl)piperazine-1-sulfo...) Show SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C21H24ClN3O4S/c1-15-19(16-5-3-2-4-6-16)21(15,20(26)27)23-30(28,29)25-13-11-24(12-14-25)18-9-7-17(22)8-10-18/h2-10,15,19,23H,11-14H2,1H3,(H,26,27)/t15-,19-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant TACE after 60 mins by fluorescence plate reader				J Med Chem 54: 2839-63 (2011) Article DOI: 10.1021/jm101609j BindingDB Entry DOI: 10.7270/Q2N87B3D
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50341822 ((1S,2R,3R)-1-[4-(4-Chlorophenyl)piperazine-1-sulfo...) Show SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C21H24ClN3O4S/c1-15-19(16-5-3-2-4-6-16)21(15,20(26)27)23-30(28,29)25-13-11-24(12-14-25)18-9-7-17(22)8-10-18/h2-10,15,19,23H,11-14H2,1H3,(H,26,27)/t15-,19-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate reader				J Med Chem 54: 2839-63 (2011) Article DOI: 10.1021/jm101609j BindingDB Entry DOI: 10.7270/Q2N87B3D
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50341822 ((1S,2R,3R)-1-[4-(4-Chlorophenyl)piperazine-1-sulfo...) Show SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C21H24ClN3O4S/c1-15-19(16-5-3-2-4-6-16)21(15,20(26)27)23-30(28,29)25-13-11-24(12-14-25)18-9-7-17(22)8-10-18/h2-10,15,19,23H,11-14H2,1H3,(H,26,27)/t15-,19-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate reader				J Med Chem 54: 2839-63 (2011) Article DOI: 10.1021/jm101609j BindingDB Entry DOI: 10.7270/Q2N87B3D
					More data for this Ligand-Target Pair