BDBM50342969 CHEMBL1770634::rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-(2-(3-chlorophenyl)piperidin-1-yl)-2,3-dihydroxy-4-oxobutanamide

SMILES: C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCCC1c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1

InChI Key: InChIKey=JOZFAGBSZGGXDH-WRJCVHQSSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50342969 (CHEMBL1770634 | rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazo...) Show SMILES C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCCC1c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1 |r| Show InChI InChI=1S/C26H29ClN4O4/c1-17(18-9-11-21(12-10-18)31-15-5-13-28-31)29-25(34)23(32)24(33)26(35)30-14-3-2-8-22(30)19-6-4-7-20(27)16-19/h4-7,9-13,15-17,22-24,32-33H,2-3,8,14H2,1H3,(H,29,34)/t17-,22?,23-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE				Bioorg Med Chem Lett 21: 3172-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.002 BindingDB Entry DOI: 10.7270/Q28P60T1
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