BDBM50343092 CHEMBL1771449::N-(3-ethylphenyl)-4-o-tolyl-2-(4-(trifluoromethyl)phenyl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide

SMILES: CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2C)-c2ccc(cc2)C(F)(F)F)c1

InChI Key: InChIKey=CAVJYPQRQJHVEV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 14 (Mus musculus)	BDBM50343092 (CHEMBL1771449 | N-(3-ethylphenyl)-4-o-tolyl-2-(4-(...) Show SMILES CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2C)-c2ccc(cc2)C(F)(F)F)c1 Show InChI InChI=1S/C30H27F3N4O/c1-3-20-8-6-9-23(17-20)34-29(38)37-16-15-26-25(18-37)27(24-10-5-4-7-19(24)2)36-28(35-26)21-11-13-22(14-12-21)30(31,32)33/h4-14,17H,3,15-16,18H2,1-2H3,(H,34,38)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...				Bioorg Med Chem Lett 21: 2832-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.084 BindingDB Entry DOI: 10.7270/Q20865N7
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