BDBM50343096 CHEMBL1771230::N-phenyl-2-(pyridin-3-yl)-4-o-tolyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide

SMILES: Cc1ccccc1-c1nc(nc2CCN(Cc12)C(=O)Nc1ccccc1)-c1cccnc1

InChI Key: InChIKey=GIODXTFZELVTOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 14 (Mus musculus)	BDBM50343096 (CHEMBL1771230 | N-phenyl-2-(pyridin-3-yl)-4-o-toly...) Show SMILES Cc1ccccc1-c1nc(nc2CCN(Cc12)C(=O)Nc1ccccc1)-c1cccnc1 Show InChI InChI=1S/C26H23N5O/c1-18-8-5-6-12-21(18)24-22-17-31(26(32)28-20-10-3-2-4-11-20)15-13-23(22)29-25(30-24)19-9-7-14-27-16-19/h2-12,14,16H,13,15,17H2,1H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...				Bioorg Med Chem Lett 21: 2832-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.084 BindingDB Entry DOI: 10.7270/Q20865N7
					More data for this Ligand-Target Pair