BDBM50343114 4-(3-chlorophenyl)-N-(3-ethylphenyl)-2-(pyridin-3-yl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide::CHEMBL1771249

SMILES: CCc1cccc(NC(=O)N2CCc3nc(nc(-c4cccc(Cl)c4)c3C2)-c2cccnc2)c1

InChI Key: InChIKey=LGJFKJZACFWJMH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 14 (Mus musculus)	BDBM50343114 (4-(3-chlorophenyl)-N-(3-ethylphenyl)-2-(pyridin-3-...) Show SMILES CCc1cccc(NC(=O)N2CCc3nc(nc(-c4cccc(Cl)c4)c3C2)-c2cccnc2)c1 Show InChI InChI=1S/C27H24ClN5O/c1-2-18-6-3-10-22(14-18)30-27(34)33-13-11-24-23(17-33)25(19-7-4-9-21(28)15-19)32-26(31-24)20-8-5-12-29-16-20/h3-10,12,14-16H,2,11,13,17H2,1H3,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...				Bioorg Med Chem Lett 21: 2832-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.084 BindingDB Entry DOI: 10.7270/Q20865N7
					More data for this Ligand-Target Pair