BDBM50343117 CHEMBL1771436::N-(3-ethylphenyl)-4-(2-methoxyphenyl)-2-(pyridin-3-yl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide

SMILES: CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2OC)-c2cccnc2)c1

InChI Key: InChIKey=TYUJLENLIPTJME-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 14 (Mus musculus)	BDBM50343117 (CHEMBL1771436 | N-(3-ethylphenyl)-4-(2-methoxyphen...) Show SMILES CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2OC)-c2cccnc2)c1 Show InChI InChI=1S/C28H27N5O2/c1-3-19-8-6-10-21(16-19)30-28(34)33-15-13-24-23(18-33)26(22-11-4-5-12-25(22)35-2)32-27(31-24)20-9-7-14-29-17-20/h4-12,14,16-17H,3,13,15,18H2,1-2H3,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...				Bioorg Med Chem Lett 21: 2832-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.084 BindingDB Entry DOI: 10.7270/Q20865N7
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