null

SMILES: Clc1cccc(N2CCN(CCCCOc3ccc4ccc(=O)[nH]c4n3)CC2)c1Cl

InChI Key: InChIKey=XBWNTYFNUFPCHL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50343261 (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4ccc(=O)[nH]c4n3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N4O2/c23-17-4-3-5-18(21(17)24)28-13-11-27(12-14-28)10-1-2-15-30-20-9-7-16-6-8-19(29)25-22(16)26-20/h3-9H,1-2,10-15H2,(H,25,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2621-5 (2011) Article DOI: 10.1016/j.bmcl.2011.01.059 BindingDB Entry DOI: 10.7270/Q29K4BJ3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50343261 (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4ccc(=O)[nH]c4n3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N4O2/c23-17-4-3-5-18(21(17)24)28-13-11-27(12-14-28)10-1-2-15-30-20-9-7-16-6-8-19(29)25-22(16)26-20/h3-9H,1-2,10-15H2,(H,25,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human 5HT2A receptor				Bioorg Med Chem Lett 21: 2621-5 (2011) Article DOI: 10.1016/j.bmcl.2011.01.059 BindingDB Entry DOI: 10.7270/Q29K4BJ3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50343261 (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4ccc(=O)[nH]c4n3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N4O2/c23-17-4-3-5-18(21(17)24)28-13-11-27(12-14-28)10-1-2-15-30-20-9-7-16-6-8-19(29)25-22(16)26-20/h3-9H,1-2,10-15H2,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cells				Bioorg Med Chem Lett 21: 2621-5 (2011) Article DOI: 10.1016/j.bmcl.2011.01.059 BindingDB Entry DOI: 10.7270/Q29K4BJ3
					More data for this Ligand-Target Pair