BDBM50343347 2-Cyclopropyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-ethanone::CHEMBL1773960

SMILES: O=C(CC1CC1)N1CCC(CC1)c1nc(no1)-c1cccs1

InChI Key: InChIKey=JQYBLPMEQJNZKG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional repressor EthR (EthR) (Mycobacterium tuberculosis)	BDBM50343347 (2-Cyclopropyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiaz...) Show SMILES O=C(CC1CC1)N1CCC(CC1)c1nc(no1)-c1cccs1 Show InChI InChI=1S/C16H19N3O2S/c20-14(10-11-3-4-11)19-7-5-12(6-8-19)16-17-15(18-21-16)13-2-1-9-22-13/h1-2,9,11-12H,3-8,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
					More data for this Ligand-Target Pair