BDBM50343692 (5-(3-methoxyphenyl)-6-p-tolylpyrazin-2-yl)(4-(naphthalen-2-yl)piperazin-1-yl)methanone::CHEMBL1773880

SMILES: COc1cccc(c1)-c1ncc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1ccc2ccccc2c1

InChI Key: InChIKey=ZKAUKODVIUTKCL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50343692 ((5-(3-methoxyphenyl)-6-p-tolylpyrazin-2-yl)(4-(nap...) Show SMILES COc1cccc(c1)-c1ncc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C33H30N4O2/c1-23-10-12-25(13-11-23)32-31(27-8-5-9-29(21-27)39-2)34-22-30(35-32)33(38)37-18-16-36(17-19-37)28-15-14-24-6-3-4-7-26(24)20-28/h3-15,20-22H,16-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Inc. Curated by ChEMBL					Assay Description Displacement of [I125]-CCK8 from human CCK1 receptor expressed in CHO Flip cells after 2 hrs by scintillation counting				Bioorg Med Chem Lett 21: 2911-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.069 BindingDB Entry DOI: 10.7270/Q2TB177X
					More data for this Ligand-Target Pair