BDBM50343694 (5-(3-methoxyphenyl)-6-p-tolylpyridin-2-yl)(4-(naphthalen-2-yl)piperazin-1-yl)methanone::CHEMBL1773882

SMILES: COc1cccc(c1)-c1ccc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1ccc2ccccc2c1

InChI Key: InChIKey=FRBYTNUSHYIWDT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50343694 ((5-(3-methoxyphenyl)-6-p-tolylpyridin-2-yl)(4-(nap...) Show SMILES COc1cccc(c1)-c1ccc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C34H31N3O2/c1-24-10-12-26(13-11-24)33-31(28-8-5-9-30(23-28)39-2)16-17-32(35-33)34(38)37-20-18-36(19-21-37)29-15-14-25-6-3-4-7-27(25)22-29/h3-17,22-23H,18-21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Inc. Curated by ChEMBL					Assay Description Displacement of [I125]-CCK8 from human CCK1 receptor expressed in CHO Flip cells after 2 hrs by scintillation counting				Bioorg Med Chem Lett 21: 2911-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.069 BindingDB Entry DOI: 10.7270/Q2TB177X
					More data for this Ligand-Target Pair