BDBM50345256 5-bromo-7-(2-oxo-2-(piperazin-1-yl)ethoxy)benzofuran-2-carboxylic acid::CHEMBL1782527

SMILES: OC(=O)c1cc2cc(Br)cc(OCC(=O)N3CCNCC3)c2o1

InChI Key: InChIKey=UUMWILYFWAHJMP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50345256 (5-bromo-7-(2-oxo-2-(piperazin-1-yl)ethoxy)benzofur...) Show SMILES OC(=O)c1cc2cc(Br)cc(OCC(=O)N3CCNCC3)c2o1 Show InChI InChI=1S/C15H15BrN2O5/c16-10-5-9-6-12(15(20)21)23-14(9)11(7-10)22-8-13(19)18-3-1-17-2-4-18/h5-7,17H,1-4,8H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Inhibition of human Pim2 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 90 mins by off-chip mobility shift method				Bioorg Med Chem Lett 21: 3050-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.030 BindingDB Entry DOI: 10.7270/Q2ZP46GG
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50345256 (5-bromo-7-(2-oxo-2-(piperazin-1-yl)ethoxy)benzofur...) Show SMILES OC(=O)c1cc2cc(Br)cc(OCC(=O)N3CCNCC3)c2o1 Show InChI InChI=1S/C15H15BrN2O5/c16-10-5-9-6-12(15(20)21)23-14(9)11(7-10)22-8-13(19)18-3-1-17-2-4-18/h5-7,17H,1-4,8H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift method				Bioorg Med Chem Lett 21: 3050-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.030 BindingDB Entry DOI: 10.7270/Q2ZP46GG
					More data for this Ligand-Target Pair