BDBM50345470 2-Oxo-2-(2,2,3,3,3-pentafluoropropoxy)ethyl 3-(Allylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxylate::CHEMBL1784742

SMILES: FC(F)(F)C(F)(F)COC(=O)COC(=O)c1c2c3ccc(SCC=C)c4cccc(c2nc1=O)c34

InChI Key: InChIKey=NVVXFTANYNUPOQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50345470 (2-Oxo-2-(2,2,3,3,3-pentafluoropropoxy)ethyl 3-(All...) Show SMILES FC(F)(F)C(F)(F)COC(=O)COC(=O)c1c2c3ccc(SCC=C)c4cccc(c2nc1=O)c34 Show InChI InChI=1S/C23H14F5NO5S/c1-2-8-35-14-7-6-12-16-11(14)4-3-5-13(16)19-17(12)18(20(31)29-19)21(32)33-9-15(30)34-10-22(24,25)23(26,27)28/h2-7H,1,8-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	424	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISA				J Med Chem 54: 3732-45 (2011) Article DOI: 10.1021/jm200258t BindingDB Entry DOI: 10.7270/Q29W0FTH
					More data for this Ligand-Target Pair