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SMILES: OC(=O)Cc1ccc(CNC(=O)c2cc(cs2)-c2ccc(cc2)-c2ccccc2O)cc1

InChI Key: InChIKey=CXLJHZLYJXTAEL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346325   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage metalloelastase


(Homo sapiens (Human))		BDBM50346325
PNG
(2-(4-((4-(2'-hydroxybiphenyl-4-yl)thiophene-2-carb...)
Show SMILES OC(=O)Cc1ccc(CNC(=O)c2cc(cs2)-c2ccc(cc2)-c2ccccc2O)cc1
Show InChI InChI=1S/C26H21NO4S/c28-23-4-2-1-3-22(23)20-11-9-19(10-12-20)21-14-24(32-16-21)26(31)27-15-18-7-5-17(6-8-18)13-25(29)30/h1-12,14,16,28H,13,15H2,(H,27,31)(H,29,30)
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MMDB

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Article
PubMed
n/an/a 90n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of MMP12

J Med Chem 54: 1539-54 (2011)


Article DOI: 10.1021/jm101356p
BindingDB Entry DOI: 10.7270/Q27S7P30
More data for this
Ligand-Target Pair