BDBM50347919 CHEMBL1802487

SMILES: O=C1Cc2ccc(Oc3ccc4CC(=O)Nc4c3)cc2N1

InChI Key: InChIKey=LGJQFSLZOOSXTP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interferon-induced, double-stranded RNA-activated protein kinase (Homo sapiens (Human))	BDBM50347919 (CHEMBL1802487) Show SMILES O=C1Cc2ccc(Oc3ccc4CC(=O)Nc4c3)cc2N1 Show InChI InChI=1S/C16H12N2O3/c19-15-5-9-1-3-11(7-13(9)17-15)21-12-4-2-10-6-16(20)18-14(10)8-12/h1-4,7-8H,5-6H2,(H,17,19)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay				Bioorg Med Chem Lett 21: 4108-14 (2011) Article DOI: 10.1016/j.bmcl.2011.04.149 BindingDB Entry DOI: 10.7270/Q2KK9C4H
					More data for this Ligand-Target Pair