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SMILES: [#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7](-[#6]-[#6]-[#7])-[#6]-[#6](-[#7])=O

InChI Key: InChIKey=UGCQUVSJVBHJBO-JPRYDEJLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347963   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50347963
PNG
(CHEMBL1800267)
Show SMILES [#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7](-[#6]-[#6]-[#7])-[#6]-[#6](-[#7])=O |r|
Show InChI InChI=1S/C48H88N18O9/c1-4-11-34(61-42(71)35(13-10-23-59-48(56)57)60-40(69)29-65(24-8-6-5-7-20-49)45(74)33(52)12-9-22-58-47(54)55)41(70)63-37(26-31-15-17-32(67)18-16-31)43(72)64-38(27-51)44(73)62-36(19-14-30(2)3)46(75)66(25-21-50)28-39(53)68/h15-18,30,33-38,67H,4-14,19-29,49-52H2,1-3H3,(H2,53,68)(H,60,69)(H,61,71)(H,62,73)(H,63,70)(H,64,72)(H4,54,55,58)(H4,56,57,59)/t33-,34-,35-,36-,37-,38-/m0/s1
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n/an/a 320n/an/an/an/an/an/a



The Hebrew University of Jerusalem

Curated by ChEMBL


Assay Description
Inhibition of Akt using RPRTSSF peptide and [gamma32]ATP by cell-free radioactive assay

J Med Chem 54: 5154-64 (2011)


Article DOI: 10.1021/jm2003969
BindingDB Entry DOI: 10.7270/Q26D5TBX
More data for this
Ligand-Target Pair