BDBM50348314 CHEMBL1800220::US8772288, 8
SMILES: Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCCC2)c1)C(=O)NC1CCC1
InChI Key: InChIKey=QDXZWDYPZCHAEI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50348314 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50348314
![PNG](/data/jpeg/tenK5034/BindingDB_50348314.png) (CHEMBL1800220 | US8772288, 8)Show SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCCC2)c1)C(=O)NC1CCC1 Show InChI InChI=1S/C24H26N2O2/c1-15-7-8-17(22(27)25-18-5-4-6-18)13-19(15)16-9-10-20-21(14-16)26-23(28)24(20)11-2-3-12-24/h7-10,13-14,18H,2-6,11-12H2,1H3,(H,25,27)(H,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer
Curated by ChEMBL
| Assay Description Inhibition of human p38alpha by FRET assay |
Bioorg Med Chem Lett 21: 4130-3 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.114 BindingDB Entry DOI: 10.7270/Q2NP25DM |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50348314
![PNG](/data/jpeg/tenK5034/BindingDB_50348314.png) (CHEMBL1800220 | US8772288, 8)Show SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCCC2)c1)C(=O)NC1CCC1 Show InChI InChI=1S/C24H26N2O2/c1-15-7-8-17(22(27)25-18-5-4-6-18)13-19(15)16-9-10-20-21(14-16)26-23(28)24(20)11-2-3-12-24/h7-10,13-14,18H,2-6,11-12H2,1H3,(H,25,27)(H,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| US Patent
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall, S.A.
US Patent
| Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ... |
US Patent US8772288 (2014)
BindingDB Entry DOI: 10.7270/Q2T152BM |
More data for this Ligand-Target Pair | |