BDBM50348316 CHEMBL1800919::US8772288, 4

SMILES: CC(C)NC(=O)c1ccc(C)c(c1)-c1ccc2c(NC(=O)C22CCCC2)c1

InChI Key: InChIKey=WMHJTATUVGNFOU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50348316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50348316 (CHEMBL1800919 | US8772288, 4) Show SMILES CC(C)NC(=O)c1ccc(C)c(c1)-c1ccc2c(NC(=O)C22CCCC2)c1 Show InChI InChI=1S/C23H26N2O2/c1-14(2)24-21(26)17-7-6-15(3)18(12-17)16-8-9-19-20(13-16)25-22(27)23(19)10-4-5-11-23/h6-9,12-14H,4-5,10-11H2,1-3H3,(H,24,26)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human p38alpha by FRET assay				Bioorg Med Chem Lett 21: 4130-3 (2011) Article DOI: 10.1016/j.bmcl.2011.05.114 BindingDB Entry DOI: 10.7270/Q2NP25DM
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50348316 (CHEMBL1800919 | US8772288, 4) Show SMILES CC(C)NC(=O)c1ccc(C)c(c1)-c1ccc2c(NC(=O)C22CCCC2)c1 Show InChI InChI=1S/C23H26N2O2/c1-14(2)24-21(26)17-7-6-15(3)18(12-17)16-8-9-19-20(13-16)25-22(27)23(19)10-4-5-11-23/h6-9,12-14H,4-5,10-11H2,1-3H3,(H,24,26)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.5	25
Almirall, S.A. US Patent					Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...				US Patent US8772288 (2014) BindingDB Entry DOI: 10.7270/Q2T152BM
					More data for this Ligand-Target Pair