BDBM50348337 CHEMBL1800232

SMILES: COc1cc(\C=N\NC(=O)CSc2ccc3ccccc3n2)cc(OC)c1OC

InChI Key: InChIKey=OKKYMJZFJHIJIJ-WSDLNYQXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50348337 (CHEMBL1800232) Show SMILES COc1cc(\C=N\NC(=O)CSc2ccc3ccccc3n2)cc(OC)c1OC Show InChI InChI=1S/C21H21N3O4S/c1-26-17-10-14(11-18(27-2)21(17)28-3)12-22-24-19(25)13-29-20-9-8-15-6-4-5-7-16(15)23-20/h4-12H,13H2,1-3H3,(H,24,25)/b22-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A assessed as inhibition of hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 21: 4155-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.100 BindingDB Entry DOI: 10.7270/Q2CJ8FRT
					More data for this Ligand-Target Pair