null

SMILES: Cc1cc2[C@H](CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)C(=O)NCC(F)(F)F

InChI Key: InChIKey=CFTPYNUSGDCEFZ-WEWMWRJBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50348567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50348567 (CHEMBL1801125) Show SMILES Cc1cc2[C@H](CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)C(=O)NCC(F)(F)F |r| Show InChI InChI=1S/C35H43ClF5N3O2/c1-20-13-23-26(15-28(20)36)34(16-27(23)33(5,6)31(46)42-19-35(39,40)41)9-11-43(12-10-34)30(45)25-18-44(32(2,3)4)17-24(25)22-8-7-21(37)14-29(22)38/h7-8,13-15,24-25,27H,9-12,16-19H2,1-6H3,(H,42,46)/t24-,25+,27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation counting				Bioorg Med Chem Lett 20: 4399-405 (2010) Article DOI: 10.1016/j.bmcl.2010.06.062 BindingDB Entry DOI: 10.7270/Q23F4Q07
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50348567 (CHEMBL1801125) Show SMILES Cc1cc2[C@H](CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)C(=O)NCC(F)(F)F |r| Show InChI InChI=1S/C35H43ClF5N3O2/c1-20-13-23-26(15-28(20)36)34(16-27(23)33(5,6)31(46)42-19-35(39,40)41)9-11-43(12-10-34)30(45)25-18-44(32(2,3)4)17-24(25)22-8-7-21(37)14-29(22)38/h7-8,13-15,24-25,27H,9-12,16-19H2,1-6H3,(H,42,46)/t24-,25+,27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human MC4R expressed in CHO cells assessed as increase of alpha-MSH-stimulated cAMP release pretreated for 10 mins before alpha-M...				Bioorg Med Chem Lett 20: 4399-405 (2010) Article DOI: 10.1016/j.bmcl.2010.06.062 BindingDB Entry DOI: 10.7270/Q23F4Q07
					More data for this Ligand-Target Pair