BDBM50349909 CHEMBL1814718

SMILES: CC(C([O-])=O)c1ccc(CC2CCCC2=O)c(c1)-c1ccc(cc1)C([O-])=O

InChI Key: InChIKey=WROFRVATIQLXLH-UHFFFAOYSA-L

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50349909 (CHEMBL1814718) Show SMILES CC(C([O-])=O)c1ccc(CC2CCCC2=O)c(c1)-c1ccc(cc1)C([O-])=O Show InChI InChI=1S/C22H22O5/c1-13(21(24)25)16-9-10-17(11-18-3-2-4-20(18)23)19(12-16)14-5-7-15(8-6-14)22(26)27/h5-10,12-13,18H,2-4,11H2,1H3,(H,24,25)(H,26,27)/p-2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIA				Bioorg Med Chem 19: 3299-311 (2011) Article DOI: 10.1016/j.bmc.2011.04.050 BindingDB Entry DOI: 10.7270/Q2NZ881Z
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50349909 (CHEMBL1814718) Show SMILES CC(C([O-])=O)c1ccc(CC2CCCC2=O)c(c1)-c1ccc(cc1)C([O-])=O Show InChI InChI=1S/C22H22O5/c1-13(21(24)25)16-9-10-17(11-18-3-2-4-20(18)23)19(12-16)14-5-7-15(8-6-14)22(26)27/h5-10,12-13,18H,2-4,11H2,1H3,(H,24,25)(H,26,27)/p-2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIA				Bioorg Med Chem 19: 3299-311 (2011) Article DOI: 10.1016/j.bmc.2011.04.050 BindingDB Entry DOI: 10.7270/Q2NZ881Z
					More data for this Ligand-Target Pair