BDBM50350292 CHEMBL1812538

SMILES: COc1cccc(\C=C\c2c[nH]c3cc(F)ccc23)c1

InChI Key: InChIKey=MYJRHNOGJGLUCL-AATRIKPKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 2,3-dioxygenase (Mus musculus)	BDBM50350292 (CHEMBL1812538) Show SMILES COc1cccc(\C=C\c2c[nH]c3cc(F)ccc23)c1 Show InChI InChI=1S/C17H14FNO/c1-20-15-4-2-3-12(9-15)5-6-13-11-19-17-10-14(18)7-8-16(13)17/h2-11,19H,1H3/b6-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...				J Med Chem 54: 5320-34 (2011) Article DOI: 10.1021/jm2006782 BindingDB Entry DOI: 10.7270/Q2RF5W11
					More data for this Ligand-Target Pair