BDBM50350423 CHEMBL466154

SMILES: Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12

InChI Key: InChIKey=AQZHBCDRWFMXIN-UHFFFAOYSA-N

Data: 16 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50350423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant Aurora-b assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
NUAK family SNF1-like kinase 1 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant ARK5 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant AKT1 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant AXL assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant FAK assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant IGF1-R assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of wild type MEK1 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of wild type MET assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Nek2 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant NEK2 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Nek6 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant NEK6 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant PLK1 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant PRK1 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant SRC assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant VEGF-R2 assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50350423 (CHEMBL466154) Show SMILES Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 Show InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t Curated by ChEMBL					Assay Description Inhibition of recombinant ALK assessed as 33Pi incorporation after 60 mins by scintillation counting				Bioorg Med Chem 19: 4644-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.013 BindingDB Entry DOI: 10.7270/Q2X92BNH
					More data for this Ligand-Target Pair