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BDBM50351053 CHEMBL1819467

SMILES: Clc1ccccc1N1CCN(CCn2c(=O)[nH]c3[nH]c(cc3c2=O)-c2ccc(OCc3ccccc3)cc2)CC1

InChI Key: InChIKey=PKIRMEVDVOKPGU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351053   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50351053
PNG
(CHEMBL1819467)
Show SMILES Clc1ccccc1N1CCN(CCn2c(=O)[nH]c3[nH]c(cc3c2=O)-c2ccc(OCc3ccccc3)cc2)CC1
Show InChI InChI=1S/C31H30ClN5O3/c32-26-8-4-5-9-28(26)36-17-14-35(15-18-36)16-19-37-30(38)25-20-27(33-29(25)34-31(37)39)23-10-12-24(13-11-23)40-21-22-6-2-1-3-7-22/h1-13,20,33H,14-19,21H2,(H,34,39)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometry

Bioorg Med Chem 19: 5260-76 (2011)


Article DOI: 10.1016/j.bmc.2011.06.043
BindingDB Entry DOI: 10.7270/Q2D50NBD
More data for this
Ligand-Target Pair