BDBM50351221 CHEMBL1818409

SMILES: CC(CCc1ccccc1)NC(=O)Nc1cccc(c1F)C(F)(F)F

InChI Key: InChIKey=XZTLBORGNXPPKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50351221 (CHEMBL1818409) Show SMILES CC(CCc1ccccc1)NC(=O)Nc1cccc(c1F)C(F)(F)F Show InChI InChI=1S/C18H18F4N2O/c1-12(10-11-13-6-3-2-4-7-13)23-17(25)24-15-9-5-8-14(16(15)19)18(20,21)22/h2-9,12H,10-11H2,1H3,(H2,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate after 10 mins by fluorescent assay				Bioorg Med Chem 19: 5585-95 (2011) Article DOI: 10.1016/j.bmc.2011.07.034 BindingDB Entry DOI: 10.7270/Q2V69JZ1
					More data for this Ligand-Target Pair