BDBM50351285 CHEMBL1818769

SMILES: O=C1N(C(Cc2ccccc2)Nc2ccc(cc12)N1CCOCC1)c1ccccc1

InChI Key: InChIKey=SFSSRJPKWHRSFA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50351285 (CHEMBL1818769) Show SMILES O=C1N(C(Cc2ccccc2)Nc2ccc(cc12)N1CCOCC1)c1ccccc1 Show InChI InChI=1S/C25H25N3O2/c29-25-22-18-21(27-13-15-30-16-14-27)11-12-23(22)26-24(17-19-7-3-1-4-8-19)28(25)20-9-5-2-6-10-20/h1-12,18,24,26H,13-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair