BDBM50351295 CHEMBL1818781

SMILES: CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccccc3Cl)ccc2C1

InChI Key: InChIKey=KTDMCLCTLWFDGI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50351295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50351295 (CHEMBL1818781) Show SMILES CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccccc3Cl)ccc2C1 Show InChI InChI=1S/C26H27ClN2O/c1-29(2)17-18-7-8-22-16-23(14-13-21(22)15-18)28-26(30)20-11-9-19(10-12-20)24-5-3-4-6-25(24)27/h3-6,9-14,16,18H,7-8,15,17H2,1-2H3,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 19: 5539-52 (2011) Article DOI: 10.1016/j.bmc.2011.07.038 BindingDB Entry DOI: 10.7270/Q26H4HT4
					More data for this Ligand-Target Pair
GPR24 (RAT)	BDBM50351295 (CHEMBL1818781) Show SMILES CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccccc3Cl)ccc2C1 Show InChI InChI=1S/C26H27ClN2O/c1-29(2)17-18-7-8-22-16-23(14-13-21(22)15-18)28-26(30)20-11-9-19(10-12-20)24-5-3-4-6-25(24)27/h3-6,9-14,16,18H,7-8,15,17H2,1-2H3,(H,28,30)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 19: 5539-52 (2011) Article DOI: 10.1016/j.bmc.2011.07.038 BindingDB Entry DOI: 10.7270/Q26H4HT4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50351295 (CHEMBL1818781) Show SMILES CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccccc3Cl)ccc2C1 Show InChI InChI=1S/C26H27ClN2O/c1-29(2)17-18-7-8-22-16-23(14-13-21(22)15-18)28-26(30)20-11-9-19(10-12-20)24-5-3-4-6-25(24)27/h3-6,9-14,16,18H,7-8,15,17H2,1-2H3,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced GTPgammaS binding after 60 mins by scintillation coun...				Bioorg Med Chem 19: 5539-52 (2011) Article DOI: 10.1016/j.bmc.2011.07.038 BindingDB Entry DOI: 10.7270/Q26H4HT4
					More data for this Ligand-Target Pair