BDBM50351315 CHEMBL1818803

SMILES: CNCC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1

InChI Key: InChIKey=GPXYOCKQAQTLCJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50351315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GPR24 (RAT)	BDBM50351315 (CHEMBL1818803) Show SMILES CNCC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 |t:3| Show InChI InChI=1S/C25H23ClN2O/c1-27-16-17-2-3-22-15-24(13-10-21(22)14-17)28-25(29)20-6-4-18(5-7-20)19-8-11-23(26)12-9-19/h4-15,27H,2-3,16H2,1H3,(H,28,29)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 19: 5539-52 (2011) Article DOI: 10.1016/j.bmc.2011.07.038 BindingDB Entry DOI: 10.7270/Q26H4HT4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50351315 (CHEMBL1818803) Show SMILES CNCC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 |t:3| Show InChI InChI=1S/C25H23ClN2O/c1-27-16-17-2-3-22-15-24(13-10-21(22)14-17)28-25(29)20-6-4-18(5-7-20)19-8-11-23(26)12-9-19/h4-15,27H,2-3,16H2,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 19: 5539-52 (2011) Article DOI: 10.1016/j.bmc.2011.07.038 BindingDB Entry DOI: 10.7270/Q26H4HT4
					More data for this Ligand-Target Pair