BDBM50351326 CHEMBL1817681

SMILES: CN(CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1)c1ccccc1

InChI Key: InChIKey=VIMHLPANVVNLHI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50351326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50351326 (CHEMBL1817681) Show SMILES CN(CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1)c1ccccc1 |t:3| Show InChI InChI=1S/C31H27ClN2O/c1-34(30-5-3-2-4-6-30)21-22-7-8-27-20-29(18-15-26(27)19-22)33-31(35)25-11-9-23(10-12-25)24-13-16-28(32)17-14-24/h2-6,9-20H,7-8,21H2,1H3,(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced GTPgammaS binding after 60 mins by scintillation coun...				Bioorg Med Chem 19: 5539-52 (2011) Article DOI: 10.1016/j.bmc.2011.07.038 BindingDB Entry DOI: 10.7270/Q26H4HT4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50351326 (CHEMBL1817681) Show SMILES CN(CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1)c1ccccc1 |t:3| Show InChI InChI=1S/C31H27ClN2O/c1-34(30-5-3-2-4-6-30)21-22-7-8-27-20-29(18-15-26(27)19-22)33-31(35)25-11-9-23(10-12-25)24-13-16-28(32)17-14-24/h2-6,9-20H,7-8,21H2,1H3,(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 19: 5539-52 (2011) Article DOI: 10.1016/j.bmc.2011.07.038 BindingDB Entry DOI: 10.7270/Q26H4HT4
					More data for this Ligand-Target Pair
GPR24 (RAT)	BDBM50351326 (CHEMBL1817681) Show SMILES CN(CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1)c1ccccc1 |t:3| Show InChI InChI=1S/C31H27ClN2O/c1-34(30-5-3-2-4-6-30)21-22-7-8-27-20-29(18-15-26(27)19-22)33-31(35)25-11-9-23(10-12-25)24-13-16-28(32)17-14-24/h2-6,9-20H,7-8,21H2,1H3,(H,33,35)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 19: 5539-52 (2011) Article DOI: 10.1016/j.bmc.2011.07.038 BindingDB Entry DOI: 10.7270/Q26H4HT4
					More data for this Ligand-Target Pair