BDBM50352070 CHEMBL1824040

SMILES: CC(=O)c1ccc2OCC(=O)N(CCN3CCC(CC3)NCc3ccc4OCC(=O)Nc4n3)c2c1

InChI Key: InChIKey=HJOYSJFIOFFFHQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50352070 (CHEMBL1824040) Show SMILES CC(=O)c1ccc2OCC(=O)N(CCN3CCC(CC3)NCc3ccc4OCC(=O)Nc4n3)c2c1 Show InChI InChI=1S/C25H29N5O5/c1-16(31)17-2-4-21-20(12-17)30(24(33)15-35-21)11-10-29-8-6-18(7-9-29)26-13-19-3-5-22-25(27-19)28-23(32)14-34-22/h2-5,12,18,26H,6-11,13-15H2,1H3,(H,27,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of human ERG by electrophysiological assay				Bioorg Med Chem Lett 21: 5432-5 (2011) Article DOI: 10.1016/j.bmcl.2011.06.126 BindingDB Entry DOI: 10.7270/Q2JM2B0P
					More data for this Ligand-Target Pair