BDBM50352072 CHEMBL1824028

SMILES: O=C1COc2ccc(CNC3CCN(CCN4C(=O)COc5ccc(cc45)-n4cnnn4)CC3)nc2N1

InChI Key: InChIKey=WMCQCTQIIKAREG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50352072 (CHEMBL1824028) Show SMILES O=C1COc2ccc(CNC3CCN(CCN4C(=O)COc5ccc(cc45)-n4cnnn4)CC3)nc2N1 Show InChI InChI=1S/C24H27N9O4/c34-22-13-36-21-3-1-17(27-24(21)28-22)12-25-16-5-7-31(8-6-16)9-10-32-19-11-18(33-15-26-29-30-33)2-4-20(19)37-14-23(32)35/h1-4,11,15-16,25H,5-10,12-14H2,(H,27,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of human ERG by electrophysiological assay				Bioorg Med Chem Lett 21: 5432-5 (2011) Article DOI: 10.1016/j.bmcl.2011.06.126 BindingDB Entry DOI: 10.7270/Q2JM2B0P
					More data for this Ligand-Target Pair