BDBM50352075 CHEMBL1824032

SMILES: FC(F)(F)C(=O)Nc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc3ccc4OCC(=O)Nc4n3)c2c1

InChI Key: InChIKey=ULPLMNIDEXAPFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50352075 (CHEMBL1824032) Show SMILES FC(F)(F)C(=O)Nc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc3ccc4OCC(=O)Nc4n3)c2c1 Show InChI InChI=1S/C25H27F3N6O5/c26-25(27,28)24(37)31-16-1-3-19-18(11-16)34(22(36)14-39-19)10-9-33-7-5-15(6-8-33)29-12-17-2-4-20-23(30-17)32-21(35)13-38-20/h1-4,11,15,29H,5-10,12-14H2,(H,31,37)(H,30,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of human ERG by electrophysiological assay				Bioorg Med Chem Lett 21: 5432-5 (2011) Article DOI: 10.1016/j.bmcl.2011.06.126 BindingDB Entry DOI: 10.7270/Q2JM2B0P
					More data for this Ligand-Target Pair