BDBM50352370 CHEMBL1823341

SMILES: COc1cccnc1C(=O)N1CCN(CC1)c1ccc(NC(C)(C)c2ccccc2)cc1Cl

InChI Key: InChIKey=FDJKLSHAFVLWTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50352370 (CHEMBL1823341) Show SMILES COc1cccnc1C(=O)N1CCN(CC1)c1ccc(NC(C)(C)c2ccccc2)cc1Cl Show InChI InChI=1S/C26H29ClN4O2/c1-26(2,19-8-5-4-6-9-19)29-20-11-12-22(21(27)18-20)30-14-16-31(17-15-30)25(32)24-23(33-3)10-7-13-28-24/h4-13,18,29H,14-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting				Bioorg Med Chem Lett 21: 5552-6 (2011) Article DOI: 10.1016/j.bmcl.2011.06.136 BindingDB Entry DOI: 10.7270/Q2R49R5K
					More data for this Ligand-Target Pair