BDBM50352377 CHEMBL1823348

SMILES: COC(=O)C(N1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1C)c1ccccc1

InChI Key: InChIKey=MPXULPFZPHVSDC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50352377 (CHEMBL1823348) Show SMILES COC(=O)C(N1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1C)c1ccccc1 Show InChI InChI=1S/C33H33N3O3/c1-24-23-27(34-32(37)29-16-10-9-15-28(29)25-11-5-3-6-12-25)17-18-30(24)35-19-21-36(22-20-35)31(33(38)39-2)26-13-7-4-8-14-26/h3-18,23,31H,19-22H2,1-2H3,(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting				Bioorg Med Chem Lett 21: 5552-6 (2011) Article DOI: 10.1016/j.bmcl.2011.06.136 BindingDB Entry DOI: 10.7270/Q2R49R5K
					More data for this Ligand-Target Pair