BDBM50352384 CHEMBL1823355

SMILES: CCNC(=O)C(N1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2cccnc2)cc1F)c1ccccc1

InChI Key: InChIKey=YYUXPUISOAQNJU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352384   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50352384 (CHEMBL1823355) Show SMILES CCNC(=O)C(N1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2cccnc2)cc1F)c1ccccc1 Show InChI InChI=1S/C32H32FN5O2/c1-2-35-32(40)30(23-9-4-3-5-10-23)38-19-17-37(18-20-38)29-15-14-25(21-28(29)33)36-31(39)27-13-7-6-12-26(27)24-11-8-16-34-22-24/h3-16,21-22,30H,2,17-20H2,1H3,(H,35,40)(H,36,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting				Bioorg Med Chem Lett 21: 5552-6 (2011) Article DOI: 10.1016/j.bmcl.2011.06.136 BindingDB Entry DOI: 10.7270/Q2R49R5K
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