BDBM50352814 CHEMBL1823654

SMILES: Clc1ccc(cc1Cl)C(NC(=O)c1ccc2cnccc2c1)C1CCNC1

InChI Key: InChIKey=REUCABNHPPJJRD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50352814 (CHEMBL1823654) Show SMILES Clc1ccc(cc1Cl)C(NC(=O)c1ccc2cnccc2c1)C1CCNC1 Show InChI InChI=1S/C21H19Cl2N3O/c22-18-4-3-14(10-19(18)23)20(17-6-8-25-12-17)26-21(27)15-1-2-16-11-24-7-5-13(16)9-15/h1-5,7,9-11,17,20,25H,6,8,12H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 21: 5191-6 (2011) Article DOI: 10.1016/j.bmcl.2011.07.056 BindingDB Entry DOI: 10.7270/Q21G0MNQ
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50352814 (CHEMBL1823654) Show SMILES Clc1ccc(cc1Cl)C(NC(=O)c1ccc2cnccc2c1)C1CCNC1 Show InChI InChI=1S/C21H19Cl2N3O/c22-18-4-3-14(10-19(18)23)20(17-6-8-25-12-17)26-21(27)15-1-2-16-11-24-7-5-13(16)9-15/h1-5,7,9-11,17,20,25H,6,8,12H2,(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 21: 5191-6 (2011) Article DOI: 10.1016/j.bmcl.2011.07.056 BindingDB Entry DOI: 10.7270/Q21G0MNQ
					More data for this Ligand-Target Pair