BDBM50352836 CHEMBL1823642

SMILES: Clc1cccc(C(NC(=O)c2ccc3cnccc3c2)C2CCNCC2)c1Cl

InChI Key: InChIKey=FPARTTUOOZOWFP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50352836 (CHEMBL1823642) Show SMILES Clc1cccc(C(NC(=O)c2ccc3cnccc3c2)C2CCNCC2)c1Cl Show InChI InChI=1S/C22H21Cl2N3O/c23-19-3-1-2-18(20(19)24)21(14-6-9-25-10-7-14)27-22(28)16-4-5-17-13-26-11-8-15(17)12-16/h1-5,8,11-14,21,25H,6-7,9-10H2,(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 21: 5191-6 (2011) Article DOI: 10.1016/j.bmcl.2011.07.056 BindingDB Entry DOI: 10.7270/Q21G0MNQ
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50352836 (CHEMBL1823642) Show SMILES Clc1cccc(C(NC(=O)c2ccc3cnccc3c2)C2CCNCC2)c1Cl Show InChI InChI=1S/C22H21Cl2N3O/c23-19-3-1-2-18(20(19)24)21(14-6-9-25-10-7-14)27-22(28)16-4-5-17-13-26-11-8-15(17)12-16/h1-5,8,11-14,21,25H,6-7,9-10H2,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 21: 5191-6 (2011) Article DOI: 10.1016/j.bmcl.2011.07.056 BindingDB Entry DOI: 10.7270/Q21G0MNQ
					More data for this Ligand-Target Pair