BDBM50352844 CHEMBL1823649

SMILES: COc1cc2cnccc2cc1C(=O)NC(C1CCNCC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=MJONRYHHUGUWTD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50352844 (CHEMBL1823649) Show SMILES COc1cc2cnccc2cc1C(=O)NC(C1CCNCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H23Cl2N3O2/c1-30-21-12-17-13-27-9-6-15(17)10-18(21)23(29)28-22(14-4-7-26-8-5-14)16-2-3-19(24)20(25)11-16/h2-3,6,9-14,22,26H,4-5,7-8H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 21: 5191-6 (2011) Article DOI: 10.1016/j.bmcl.2011.07.056 BindingDB Entry DOI: 10.7270/Q21G0MNQ
					More data for this Ligand-Target Pair