BDBM50353260 CHEMBL1830534

SMILES: CCCCCCCCc1nc2cc(\C=C\C(=O)NO)ccc2n1CCNC

InChI Key: InChIKey=AMIKPLQPRZKGPT-ACCUITESSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50353260 (CHEMBL1830534) Show SMILES CCCCCCCCc1nc2cc(\C=C\C(=O)NO)ccc2n1CCNC Show InChI InChI=1S/C21H32N4O2/c1-3-4-5-6-7-8-9-20-23-18-16-17(11-13-21(26)24-27)10-12-19(18)25(20)15-14-22-2/h10-13,16,22,27H,3-9,14-15H2,1-2H3,(H,24,26)/b13-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
S*BIO Pte Ltd. Curated by ChEMBL					Assay Description Inhibition of full length recombinant HDAC1 using Fluor de Lys as substrate by fluorescence assay				J Med Chem 54: 4694-720 (2011) Article DOI: 10.1021/jm2003552 BindingDB Entry DOI: 10.7270/Q29S1RD6
					More data for this Ligand-Target Pair