BDBM50353654 CHEMBL1829822

SMILES: OC(=O)CC(Cc1nc2ccc(I)cc2[nH]1)c1ccc(Cl)cc1

InChI Key: InChIKey=IFNAFTNELXGANT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C (PKC) (Homo sapiens (Human))	BDBM50353654 (CHEMBL1829822) Show SMILES OC(=O)CC(Cc1nc2ccc(I)cc2[nH]1)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClIN2O2/c18-12-3-1-10(2-4-12)11(8-17(22)23)7-16-20-14-6-5-13(19)9-15(14)21-16/h1-6,9,11H,7-8H2,(H,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNFalpha-induced NF-kB activation by luciferase reporter gene assay				J Med Chem 54: 6714-23 (2011) Article DOI: 10.1021/jm2005892 BindingDB Entry DOI: 10.7270/Q2CJ8DVR
					More data for this Ligand-Target Pair
Protein kinase C (PKC) (Homo sapiens (Human))	BDBM50353654 (CHEMBL1829822) Show SMILES OC(=O)CC(Cc1nc2ccc(I)cc2[nH]1)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClIN2O2/c18-12-3-1-10(2-4-12)11(8-17(22)23)7-16-20-14-6-5-13(19)9-15(14)21-16/h1-6,9,11H,7-8H2,(H,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human PKCzeta assessed as [gamma32P]ATP utilization using myelin basic protein as substrate				J Med Chem 54: 6714-23 (2011) Article DOI: 10.1021/jm2005892 BindingDB Entry DOI: 10.7270/Q2CJ8DVR
					More data for this Ligand-Target Pair